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Sung, Kuangsen


Molecular Simulation
Physical Organic Chemistry      

☎ Phone:06-2757575-65338


BS in Chemistry, National Chung Hsing University (1982)


MS in Pharmacy, National Defense Medical Center (1986)


PhD in Chemistry, Clemson University (1992)


1986-1987  Taipei Veterans General Hospital, Technician


1998-2000  National Cheng Kung University, Assistant Professor


2000-2003  National Cheng Kung University, Associate Professor


2003-Prensent  National Cheng Kung University, Professor


  1. Li, M. J.; Xu, J. J.; Sung, R.; Sung, K.* "Positively charged GFP-chromophore-based fluorescent sensor for DNA." Optical Materials, 2024, 153, 115581.

  2. Ke, H.W.; Sung, K."7-membered-ring effect on fluorescence quantum yield: does metal-complexation-induced twisting-inhibition of an amino GFP chromophore derivative enhance fluorescence?" Phys. Chem. Chem. Phys.. ,2023, 25, 14627-14634.

  3. Liao, J.W.; Sung, R.B.; Sung, K.* "Against the NEER principle: the third type of photochromism for GFP chromophore derivatives" Phys. Chem. Chem. Phys. ,2022, 24, 295-304.

  4. Ming-Ju Li;Yen-Hsun Lin; Robert Sung; Kuangsen Sung* "E–Z Isomerization Mechanism of the Green Fluorescent Protein Chromophore: Remote Regulation by Proton Dissociation of the Phenol Group”J. Phys. Chem. A ,2021, 125, 17, 3614–3621.

  5. Chou, C. Y.; Sung, Robert; Chang, W. L.; Sung, K.*  "A GFP-chromophore-based C3v-symmetric tripodal receptor with selective recognition of Hg(II), Fe(III) and Cr(III)”Mater. Chem. Front., 2020, 4, 1714-1719

  6. Wu, T. H.; Su, Z. S.; Sung, Robert; Sung, K.*  "Aza-ortho-Quinone methide and its conjugated acid: reactivity, stability and acidity”ChemPhysChem, 2020, 21, 307-312.

  7. Chen, Y.-H.; Sung, Robert; Sung, K.* "Dramatic changes of excited-state behaviour of green fluorescent protein chromophore by a strong π-donating group through significantly pulling down excited-state potential energy surface with photoinduced intramolecular charge transfer" Phys. Chem. Chem. Phys., 2020, 22, 2424-2428.

  8. Chen, Y.-H.; Sung, Robert; Sung, K.* "Fate of the fluorescent state of p-amido analogue of green fluorescence protein chromophore"  J. Lumin., 2019, 213, 446-450.

  9. Chen, Y. H.; Sung Robert; Sung, K.* "Why does a para-amino group make the green fluorescent protein chromophore non-fluorescent: coherent intramolecular charge transfer reduces the Z/E-photoisomerization barrier" Chem. Commun., 2019, 55, 8991-8994.

  10. Xu, J. J. ; Sung, Robert ; Sung, K.*"S1/S0 Potential Energy Surfaces Experience Different Types of Restricted Rotation: Restricted Z/E Photoisomerization and E/ZThermoisomerization by an Out-of-Plane Benzyl Group or In-Planem‐Pyridinium Group?" J. Phys. Chem. A, 2019, 123, 4708−4716.

  11. Zhang, Z.-Y.; Sung, R.; Sung, K.* "Insights into the unusual dual fluorescence of the ortho-amino analogue of green fluorescent protein chromophore" J. Lumin., 2018, 202163-167.

  12. Fanjiang, M.-W.; Li, M.-J.; Sung, R.*; Sung, K.*. "Synthesis and properties of the para-trimethylammonium analogues of green fluorescence protein (GFP) chromophore: The mimic of protonated GFP chromophore" Bioorg. Chem., 2018, 77, 300-310.

  13. Chen, Y.-H.; Sung, R.; Sung, K.*. "Synthesis and Properties of the p-Sulfonamide Analogue of the Green Fluorescent Protein (GFP) Chromophore: The Mimic of GFP Chromophore with Very Strong N-H Photoacid Strength" Org. Lett., 2018, 20, 1768-1772.

  14. Chen, Y.-H.; Sung, R.; Sung, K.*. "Insights into Excited State Intramolecular Proton Transfer: An Alternative Model for Excited State Proton Transfer of Green Fluorescence Protein" J. Phys. Chem. A, 2018122, 5931-5944.

  15. Sung, R.; Sung, K.*. "Insights into unusual stability of 5-membered-ring endocyclic benzyl carbocations in aqueous solution" J. Phys. Org. Chem., 2018202, 163-167. 

  16. Zhang, Z.-Y.; Sung, R.; Sung, K.*. "Synthetic green fluorescent protein chromophore analogues with a positive charge at the phenyl-like group" Amino Acids, 2018, 50, 141-147. 

  17. Sung, R.; Sung, K.*. "TICT excited states of o- and p-N,N-dimethylamino analogues of GFP chromophore" J. Phys. Org. Chem., 2018, 31, e3791.

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