Yeh, Chen-Sheng
Distinguished Chair Professor
1. Synthesis and formation mechanism of nanomaterials
2. Design of functional nanomaterials
3. Applications of nanomaterials:
(1) Biomedical image
(2) Drug carrier and drug delivery
(3) Therapy in cancer, vessel dilation, wound healing
✉ Email：csyeh@mail.ncku.edu.tw
☎ Phone：06-2757575-65328
Education
BS in Chemistry, Tamkang University (1984)
MS in Chemistry, National Tsing Hua University (1986)
PhD in Chemistry, University of Georgia (1993)
Experience
1995-2001 National Cheng Kung University, Associate Professor
2001-2009 National Cheng Kung University, Professor
2009-2017 National Cheng Kung University, Distinguished Professor
2017-Present National Cheng Kung University, Distinguished Chair Professor
2018-Present National Cheng Kung University, Department Chair
Publications
1.
Wang,L.C.; Chiou,P.Y.; Hsu,Y.P.; Lee,C.L.; Hung,C.H.; Wu,Y.H.; Wang,W.J.; Hsieh,G.L.; Chen,Y.C.; Chang,L.C.; Su,W.P.; Manoharan,D.; Liao,M.C.; Thangudu,S.; Li,W.P.; Su,C.H.; Tian;H.K.; Yeh, C.S. * " Prussian blue analog with separated active sites to catalyze water driven enhanced catalytic treatments"
Nature Communications, 2023, 14, 4709.
2.
Chen, Y.C.; Li, Y.T.; Lee, C.L.; Kuo, Y.T.; Ho, C.L.; Lin, W.C.; Hsu, M.C.; Long, X.; Chen, J.S.; Li, W.P.; Su, C.H.; Okamoto, A.; Yeh, C.S. * " Electroactive membrane fusion-liposome for increased electron transfer to enhance radiodynamic therapy" Nature Nanotechnology, 2023, accepted.
3.
Yagi, J. ; Ikeda, A. ; Wang, L.C. ; Yeh, C.S. *; Kawasaki, H.* " Singlet Oxygen Generation Using Thiolated Gold Nanoclusters under Photo- and Ultrasonic Excitation: Size and Ligand Effect"
J. Phys. Chem. C , 2022, 126, 46, 19693–19704.
4.
Chen, Y.C.; Liu, Y.J. ; Lee, C.L.; Pham, K.Y.; Manoharan, D.; Thangudu, S. ; Su, C.H.*; Yeh, C.S.*
" Engineering H2O2 and O-2 Self-Supplying Nanoreactor to Conduct Synergistic Chemiexcited Photodynamic and Calcium-Overloaded Therapy in Orthotopic Hepatic Tumors" Adv. Healthc. Mater., 2022, 11, 20, 2201613.
5.
Su, W.P.*; Chang, L.C.; Song, W.H.; Yang, L.X.; Wang, L.C.; Chia, Z.C.; Chin, Y.C. ; Shan, Y.S.; Huang, C.C.*; Yeh, C.S.*" Polyaniline-Based Glyco-Condensation on Au Nanoparticles Enhances Immunotherapy in Lung Cancer" ACS Appl. Mater. Interfaces, 2022, 14, 21, 24144–24159.
6.
Wang, L.C.; Chang, L.C.; Su, G.L.; Chang, P.Y.; Hsu, H.F.; Lee, C.L.; Li, J.R.; Liao, M.C.; Thangudu, S.; Treekoon, J.; Yu, C.C.; Sheu, H.S. *; Tu, T.Y. *; Su, W.P.*; Su, C.H.* ; Yeh, C.S.*" Chemical Structure and Shape Enhance MR Imaging-Guided X-ray Therapy Following Marginative Delivery"
ACS Appl. Mater. Interfaces, 2022, 14, 11, 13056–13069.
7.
Guo, L.Z.*; Wu, C.H.*; Tsai, M.F.; Cheng, F.Y. ; Shanmugam, V.; Tsai, Z.U.; Zhang, Z.M.; Liu, T.M.*; Yeh, C.S.*" Plasmon Resonant Two-Photon Luminescence Inducing Photosensitization and Nonlinear Optical Microscopy In Vivo by Near-Infrared Excitation of Au Nanopeanuts" Appl. Sci., 2021, 11, 22, 10875.
8.
Luo, C.H.*; Hsu, Y.H.; Wu, W.J.; Chang, K.C.; Yeh, C.S.*"Phage Digestion of a Bacterial Capsule Imparts Resistance to Two Antibiotic Agents" Microorganisms., 2021, 9, 4, 794.
9.
Divinah Manoharan;Li-Chan Chang;Yan-Shen Shan;Forn-Chia Lin;Lai-Chin Wu;Hwo-Shuenn Sheu;Wen-Pin Su*;Yeh, C.S.* "Synchronization of Nanoparticle Sensitization and Radiosensitizing Chemotherapy through Cell Cycle Arrest Achieving Ultralow X-ray Dose Delivery to Pancreatic Tumors" ACS Nano, 2021, 15, 5, 9084-9100.
10.
Pham, K. Y.; Wang, L. C.; Hsieh, C. C.; Hsu, Y. P.; Chang, L. C.; Su, W. P.; Chien, Y. H.*; Yeh, C. S.* "1550 nm excitation-responsive upconversion nanoparticles to establish dual-photodynamic therapy against pancreatic tumor" J. Mater. Chem. B, 2021, 9, 694-709.
11.
Kaur, K.; Bindra, P.; Mondal, S.; Li, WP; Sharma, S.; Sahu, B.K.; Naidu, B.S.; Yeh, C.S.; Gautam, U.K. ; Shanmugam, V.* “Upconversion Nanodevice-Assisted Healthy Molecular Photocorrection” ACS Biomater. Sci. Eng., 2021, 7, 1, 291–298.
12.
Lee, I. J.; Kao, P. T.; Hung, S. A.; Wang, Z. W.; Lin, H. J.; Chang, W. T.; Yeh, C. S.*; Liau, Ian* “Light triggering goldsomes enable local NO-generation and alleviate pathological vasoconstriction” Nanomedicine: NBM, 2020.
13.
Pu, Y. C.*; Wang, L. C.; Wu, S. N.; Chang, J. C.; Yeh, C. S.* "Aspect Ratio Dependent Charge Carrier Dynamics in Matchstick-like Ag2S-ZnS Nanorods for Solar Hydrogen Generation" J. Phys. Chem. Lett., 2020, 11, 2150-2157.
14.
Chen, Z. Z.; Wang, L. C.; Divinah Manoharan; Lee, C. L.; Wu, L. C.; Huang, W. T.; Huang, E. Y.; Su, C. H.*; Sheu, H. S.*; Yeh, C. S.* "Low Dose of X-Ray-Excited Long-Lasting Luminescent Concave Nanocubes in Highly Passive Targeting Deep-Seated Hepatic Tumors" Adv. Mater., 2019, 31, 1905087.
15.
Su, C. H.; Li, W. P.; Tsao, L. C.; Wang, L. C.; Hsu, Y. P.; Wang, W. J.; Liao, M. C.; Lee, C. L.; Yeh, C. S.* "Enhancing Microcirculation on Multitriggering Manner Facilitates Angiogenesis and Collagen Deposition on Wound Healing by Photoreleased NO from Hemin-Derivatized Colloids" ACS Nano, 2019, 13, 4290-4301.
16.
Divinah Manoharan; Lia, W. P.; Yeh, C. S.* "Advances in controlled gas-releasing nanomaterials for therapeutic applications" Nanoscale Horiz., 2019, 4, 557-578
17.
Kan, C. D.; Wang, J. N.*; Li, W. P.; Lin, S. H.; Chen, W. L.; Hsu, Y. P.; Yeh, C. S.* "Clinical ultrasound stimulating angiogenesis following drug-release from polymersomes on the ischemic zone for peripheral arterial occlusive disease" Nanomedicine: NBM, 2018, 14, 2205-2213.
18.
Luo, C. H.*; Yeh, C. S.* "Construction of Deoxyribonucleic Acid Decorated Gold Nanostructures as Nanomedical Agents" J. Chin. Chem. Soc., 2017, 64, 1250-1258.
19.
Li, W. P.; Su, C. H.; Wang, S. J.; Tsai, F. J.; Chang, C. T.; Liao, M. C.; Yu, C. C.; Vi Tran, T. T.; Lee, C. N.; Chiu, W. T.; Wong, T. W.*; Yeh, C. S.* "CO2 Delivery to Accelerate Incisional Wound Healing Following Single Irradiation of Near-Infrared Lamp on the Coordinated Colloids" ACS Nano, 2017, 11, 5826-5835.
20.
Kao, P. T.; Lee, I. J.; Liau, I.*; Yeh, C. S.* "Controllable NO release from Cu1.6S nanoparticle decomposition of S-nitrosoglutathiones following photothermal disintegration of polymersomes to elicit cerebral vasodilatory activity" Chem. Sci., 2017, 8, 291-297.
21.
Li, W. P.; Su, C. H.; Tsao, L. C.; Chang, C. T.; Hsu, Y. P.; Yeh, C. S.* "Controllable CO Release Following Near-Infrared Light-Induced Cleavage of Iron Carbonyl Derivatized Prussian Blue Nanoparticles for CO-Assisted Synergistic Treatment" ACS Nano, 2016, 10, 11027-11036.
22.
Huang, Y. K.; Su, C. H.; Chen, J. J.; Chang, C. T.; Tsai, Y. H.; Syu, S. F.; Tseng, T. T.; Yeh, C. S.* "Fabrication of Silica-Coated Hollow Carbon Nanospheres Encapsulating Fe3O4 Cluster for Magnetical and MR Imaging Guided NIR Light Triggering Hyperthermia and US Imaging" ACS Appl. Mater. Interfaces, 2016, 8, 14470-14480.
23.
Luo, C. H.; Huang, C. T.; Su, C. H.; Yeh, C. S.* "Bacteria-Mediated Hypoxia-Specific Delivery of Nanoparticles for Tumors Imaging and Therapy" Nano Lett., 2016, 16, 3493-3499.
Li, W. P.; Su, C. H.; Chang, C. Y.; Lin, Y. J.; Yeh, C. S.* "Ultrasound-Induced Reactive Oxygen Species-Mediated Therapy and Imaging Using a Fenton Reaction Activable Polymersome" ACS Nano, 2016, 10, 2017-2027.
24.