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Yeh, Chen-Sheng

Distinguished Chair Professor

1. Synthesis and formation mechanism of nanomaterials

2. Design of functional nanomaterials

3. Applications of nanomaterials:

(1) Biomedical image

(2) Drug carrier and drug delivery

(3) Therapy in cancer, vessel dilation, wound healing

☎ Phone:06-2757575-65328



BS in Chemistry, Tamkang University (1984)


MS in Chemistry, National Tsing Hua University (1986)


PhD in Chemistry, University of Georgia (1993)



1995-2001  National Cheng Kung University, Associate Professor


2001-2009  National Cheng Kung University, Professor


2009-2017  National Cheng Kung University, Distinguished Professor


2017-Present  National Cheng Kung University, Distinguished Chair Professor


2018-Present  National Cheng Kung University, Department Chair


  1. Wang, L. C.; Chen, H. K.; Wang, W. J.; Hsu, F. Y.; Huang, H. Z.; Kuo, R. T.; Li, W. P.*; Tian, H. K.* & Yeh, C. S.* "Boosting Upconversion Efficiency in Optically Inert Shelled Structures with Electroactive Membrane through Electron Donation." Advanced Materials, 2024, 2404120.

  2. Manoharan, D.; Wang, L. C.; Chen, Y. C.; Li, W. P.* & Yeh, C. S.* "Catalytic Nanoparticles in Biomedical Applications: Exploiting Advanced Nanozymes for Therapeutics and Diagnostics."  Advanced Healthcare Materials, 2024, 2400746.

  3. Wang, L.C.; Chiou, P.Y.; Hsu, Y.P.; Lee, C.L.; Hung, C.H.; Wu, Y.H.; Wang, W.J.; Hsieh, G.L.; Chen, Y.C.; Chang, L.C.; Su, W.P.; Manoharan, D.; Liao,M.C.; Thangudu,S.; Li, W.P.; Su, C.H.; TianH.K.; Yeh, C.S.* " Prussian blue analog with separated active sites to catalyze water driven enhanced catalytic treatments" Nature Communications, 2023, 14, 4709.

  4. Chen, Y.C.; Li, Y.T.; Lee, C.L.; Kuo, Y.T.; Ho, C.L.; Lin, W.C.; Hsu, M.C.; Long, X.; Chen, J.S.; Li, W.P.; Su, C.H.; Okamoto, A.; Yeh, C.S.* " Electroactive membrane fusion-liposome for increased electron transfer to enhance radiodynamic therapy" Nature Nanotechnology, 2023, 18, 1492-1501.

  5. Wang, L.C.; Chang, L.C.; Chen, W.Q.; Chien, Y.H.; Chang, P.Y.; Pao, C.W.; Liu, Y.F.; Sheu, H.S.; Su, W.P.; Yeh, C.H.; Yeh, C.S.* "Atomically dispersed golds on degradable zero-valent copper nanocubes augment oxygen driven Fenton-like reaction for effective orthotopic tumor therapy" Nature Communications, 2022, 13, 7772.

  6. Yagi, J. ; Ikeda, A. ; Wang, L.C. ; Yeh, C.S.*; Kawasaki, H.* " Singlet Oxygen Generation Using Thiolated Gold Nanoclusters under Photo- and Ultrasonic Excitation: Size and Ligand Effect"  J. Phys. Chem. C , 2022, 126, 46, 19693–19704.

  7. Chen, Y.C.; Liu, Y.J. ; Lee, C.L.; Pham, K.Y.; Manoharan, D.; Thangudu, S. ; Su, C.H.*; Yeh, C.S.* "Engineering H2O2 and O-2 Self-Supplying Nanoreactor to Conduct Synergistic Chemiexcited Photodynamic and Calcium-Overloaded Therapy in Orthotopic Hepatic Tumors" Adv. Healthc. Mater., 2022, 11, 20, 2201613.

  8. Su, W.P.*; Chang, L.C.; Song, W.H.; Yang, L.X.; Wang, L.C.; Chia, Z.C.; Chin, Y.C. ; Shan, Y.S.; Huang, C.C.*; Yeh, C.S.*" Polyaniline-Based Glyco-Condensation on Au Nanoparticles Enhances Immunotherapy in Lung Cancer" ACS Appl. Mater. Interfaces, 2022, 14, 21, 24144–24159.

  9. Wang, L.C.; Chang, L.C.; Su, G.L.; Chang, P.Y.; Hsu, H.F.; Lee, C.L.; Li, J.R.; Liao, M.C.; Thangudu, S.; Treekoon, J.; Yu, C.C.; Sheu, H.S. *; Tu, T.Y. *; Su, W.P.*; Su, C.H.* ; Yeh, C.S.*" Chemical Structure and Shape Enhance MR Imaging-Guided X-ray Therapy Following Marginative Delivery" ACS Appl. Mater. Interfaces, 2022, 14, 11, 13056–13069.

  10. Guo, L.Z.*; Wu, C.H.*; Tsai, M.F.; Cheng, F.Y. ; Shanmugam, V.; Tsai, Z.U.; Zhang, Z.M.; Liu, T.M.*; Yeh, C.S.*" Plasmon Resonant Two-Photon Luminescence Inducing Photosensitization and Nonlinear Optical Microscopy In Vivo by Near-Infrared Excitation of Au Nanopeanuts" Appl. Sci., 2021, 11, 22, 10875.

  11. Luo, C.H.*; Hsu, Y.H.; Wu, W.J.; Chang, K.C.; Yeh, C.S.*"Phage Digestion of a Bacterial Capsule Imparts Resistance to Two Antibiotic Agents" Microorganisms., 2021, 9, 4, 794.

  12. Divinah Manoharan; Li-Chan Chang; Yan-Shen Shan; Forn-Chia Lin; Lai-Chin Wu; Hwo-Shuenn Sheu; Wen-Pin Su*; Yeh, C.S.* "Synchronization of Nanoparticle Sensitization and Radiosensitizing Chemotherapy through Cell Cycle Arrest Achieving Ultralow X-ray Dose Delivery to Pancreatic Tumors" ACS Nano, 2021, 15, 5, 9084-9100.

  13. Pham, K. Y.; Wang, L. C.; Hsieh, C. C.; Hsu, Y. P.; Chang, L. C.; Su, W. P.; Chien, Y. H.*; Yeh, C. S.* "1550 nm excitation-responsive upconversion nanoparticles to establish dual-photodynamic therapy against pancreatic tumor" J. Mater. Chem. B, 2021, 9, 694-709.

  14. Kaur, K.; Bindra, P.; Mondal, S.; Li, WP; Sharma, S.; Sahu, B.K.; Naidu, B.S.; Yeh, C.S.; Gautam, U.K. ; Shanmugam, V.* “Upconversion Nanodevice-Assisted Healthy Molecular Photocorrection” ACS Biomater. Sci. Eng.2021, 7, 1, 291–298.

  15. Lee, I. J.; Kao, P. T.; Hung, S. A.; Wang, Z. W.; Lin, H. J.; Chang, W. T.; Yeh, C. S.*; Liau, Ian* “Light triggering goldsomes enable local NO-generation and alleviate pathological vasoconstriction” Nanomedicine: NBM 2020, 30, 10228

  16. Pu, Y. C.*; Wang, L. C.; Wu, S. N.; Chang, J. C.; Yeh, C. S.* "Aspect Ratio Dependent Charge Carrier Dynamics in Matchstick-like Ag2S-ZnS Nanorods for Solar Hydrogen Generation" J. Phys. Chem. Lett., 2020, 11, 2150-2157.

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